Ubuntu 18.04 Static Configuration Network with Netplan

nano /etc/netplan/01-network-manager-all.yaml

sudo netplan try

sudo netplan apply

# This is the network config written by 'subiquity'
network:
  ethernets:
   enp0s3:
    renderer: networkd
    dhcp4: true
   enp0s8:
    dhcp4: no
    addresses: [ 10.10.10.249/29 ]
    #      gateway4: 10.10.10.249
    nameservers:
      addresses: [ 8.8.8.8, 1.1.1.1 ]

ref:

https://linuxconfig.org/how-to-configure-static-ip-address-on-ubuntu-18-04-bionic-beaver-linux